MOTS-c: A Research Overview
MOTS-c is one of the more scientifically distinctive research peptides, and interest in it has grown quickly. This is a factual overview for a research audience — what it is, the context it's studied in, and how to confirm the vial you receive is what the label says. It is not medical guidance and makes no claim about any effect in humans.
What MOTS-c is
MOTS-c is a mitochondrial-derived peptide (MDP) — a short peptide of 16 amino acids that is unusual in that it's encoded within the mitochondrial genome rather than the nucleus. In the research literature it is studied largely in the context of mitochondrial biology and metabolic regulation, typically in cell and animal models.
| Class | Mitochondrial-derived peptide (16 amino acids) |
| Approx. molecular weight | ~2174 g/mol |
| Typical research format | Lyophilised powder, reconstituted for in-vitro work |
| Storage | -20°C, desiccated, protected from light |
Figures are nominal reference values — always defer to the Certificate of Analysis for the specific lot.
Why verification matters
MOTS-c is a niche, higher-value compound, which makes purity and identity exactly the things a supplier can cut corners on without an ordinary buyer noticing. Two vials labelled "MOTS-c" can look identical while containing very different material. What separates them is documentation:
- Identity confirmed by mass spectrometry — is this actually MOTS-c?
- Purity measured by HPLC — how much of the vial is the target peptide?
- Lot traceability — is that CoA tied to your specific batch?
For a compound studied in precise metabolic-research contexts, an unverified vial isn't just a value question — it undermines the research itself.
How DNR handles it
Every MOTS-c lot we supply ships with a batch-specific Certificate of Analysis you can verify on our site before you order — not a reused generic document. Purity is specified at ≥98% and confirmed on the lot's own CoA.
View our MOTS-c research listing →
Related reading
- What a CoA actually proves
- Mass-spectrometry identity testing explained
- Why batch verification matters
For laboratory and research use only. Not for human consumption. Nothing on this page is medical advice or a claim of any effect in humans; it summarises publicly available research context only.
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